The Function of TYMP
Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Thymidine phosphorylaseShort name:
TPAlternative name(s):
GliostatinPlatelet-derived endothelial cell growth factor
PD-ECGF
TdRPase
- RS470119 (TYMP) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
TYMP Interacts with These Diseases
Disease | Score |
Substances That Increase TYMP
Substances | Interaction | Organism | Category |
Substances That Decrease TYMP
Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|
Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
- Phosphorylase Activity
- Pyrimidine-Nucleoside Phosphorylase Activity
- Thymidine Phosphorylase Activity
- Transferase Activity, Transferring Pentosyl Groups
- Platelet-Derived Growth Factor Receptor Binding
Biological Processes:
- Angiogenesis
- Cell Differentiation
- Chemotaxis
- Pyrimidine Nucleobase Metabolic Process
- Pyrimidine Nucleoside Catabolic Process
- Pyrimidine Nucleoside Salvage
- Dna Replication
- Mitochondrial Genome Maintenance
- Pyrimidine Nucleotide Metabolic Process