• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. TWSG1

TWSG1 (Twisted gastrulation BMP signaling modulator 1)

Loading...

The Function of TWSG1

May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Twisted gastrulation protein homolog 1

Top Gene-Substance Interactions

Substances That Increase TWSG1

Substances Interaction Organism Category

Substances That Decrease TWSG1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • HNF-1A
  • HNF-1
  • STAT5A
  • TBP
  • TFIID
  • AP-2gamma
  • AP-2beta

Developmental stage:

Expressed in brain throughout development.

Biological Processes:

  • Bmp Signaling Pathway
  • Camera-Type Eye Development
  • Cell Differentiation
  • Forebrain Development
  • Hemopoiesis
  • Mesoderm Formation
  • Negative Regulation Of Bmp Signaling Pathway
  • Negative Regulation Of Osteoblast Differentiation
  • Ossification
  • Positive Regulation Of Bmp Signaling Pathway
  • Salivary Gland Morphogenesis
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 60S ribosomal protein L7| Anapl_06612| AS27_05801| AS28_10347| D17Ertd403e| EGK_09529| GW7_12041| H920_11471| M91_01442| M959_00999| MDA_GLEAN10019443| N300_05311| N301_14016| N303_01599| N305_03493| N306_04869| N307_14898| N308_00771| N309_07216| N310_06287| N312_10039| N320_10303| N321_04809| N322_05185| N325_10720| N327_05703| N328_04530| N330_09400| N331_05766| N332_09490| N333_00323| N334_04791| N335_03840| N336_00727| N340_10893| N341_03027| PAL_GLEAN10023224| PANDA_005958| TREES_T100002182| TSG| Twg| twisted gastrulation| twisted gastrulation homolog 1| twisted gastrulation homolog 1 (Drosophila)| twisted gastrulation-like 1| Twisted gastrulation like protein 1| Twisted gastrulation protein 1| Twisted gastrulation protein 1-A| twisted gastrulation protein homolog 1| Twisted gastrulation protein-like 1| Twisted gastrulation protein like protein 1| Twisted gastrulation protein-like protein 1| twsg| twsg1a| twsg1-a| twsg1-b| UY3_09406| Y956_15424| twsg1

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved