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  3. TST

TST (Thiosulfate sulfurtransferase)

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The Function of TST

Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.

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Protein names

Recommended name:

Thiosulfate sulfurtransferase

Alternative name(s):

Rhodanese

Top Gene-Substance Interactions

TST Interacts with These Diseases

Disease Score

Substances That Increase TST

Substances Interaction Organism Category

Substances That Decrease TST

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • Max
  • Arnt
  • c-Myc
  • USF1
  • USF-1

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Cysteine and methionine metabolism
  • RNA degradation
  • Sulfur relay system

Molecular Function:

  • 5s Rrna Binding
  • Thiosulfate Sulfurtransferase Activity

Biological Processes:

  • Cyanate Catabolic Process
  • Epithelial Cell Differentiation
  • Rrna Import Into Mitochondrion
  • Rrna Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| twister| rds| tst| AS28_09514| BmTST| CG10210 gene product from transcript CG10210-RA| CG10210-PA| CG10210-PB| Dmel_CG10210| EGK_03004| GW7_03678| H920_01939| I79_023362| M91_10489| MDA_GLEAN10009820| N300_11508| N302_12675| N303_09872| N305_14058| N307_05146| N308_09960| N309_04764| N320_05722| N325_04277| N327_01941| N332_00745| N333_02519| PAL_GLEAN10015399| PANDA_002478| RHODAN| rhodanese| Ski2| Ski2/tst| testis specific tektin| thiosulfate sulfurtransferase, mitochondrial| thiosulfate sulfurtransferase (rhodanese)| thiosulfate sulfurtransferase (rhodanese)-like domain containing 1| Thiosulfate sulphurtransferase (rhodanese)| TREES_T100003242| TSTD1| tst-PA| tst-PB| UY3_09704| Y1Q_012233| Y956_01176| Z169_12003

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