The Function of TOMM7
Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.
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Protein names
Recommended name:
Mitochondrial import receptor subunit TOM7 homologAlternative name(s):
Translocase of outer membrane 7 kDa subunit homolog- RS2286503 (TOMM7) ??
- RS71520386 (TOMM7) ??
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Top Gene-Substance Interactions
Substances That Increase TOMM7
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Substances That Decrease TOMM7
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Molecular Function:
Biological Processes:
- Macroautophagy
- Mitophagy In Response To Mitochondrial Depolarization
- Positive Regulation Of Protein Targeting To Mitochondrion
- Protein Import Into Mitochondrial Matrix
- Protein Import Into Mitochondrial Outer Membrane
- Protein Targeting To Mitochondrion
- Regulation Of Protein Stability