The Function of TMSB4X
Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase.
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Protein names
Recommended name:
Thymosin beta-4Alternative name(s):
T beta-4Fx
Seraspenide
- RS5979785 (TMSB4X) ??
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Top Gene-Substance Interactions
TMSB4X Interacts with These Diseases
| Disease | Score |
Substances That Increase TMSB4X
| Substances | Interaction | Organism | Category |
Substances That Decrease TMSB4X
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.
Gene Pathways:
Induction:
By alpha interferons. Decreased levels in THP-1 cells after treatment with recombinant interferon-lambda.
Molecular Function:
Biological Processes:
- Actin Cytoskeleton Organization
- Actin Filament Organization
- Platelet Degranulation
- Sequestering Of Actin Monomers
- Osteoblast Differentiation
- Regulation Of Cell Migration