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  3. TMSB4X

TMSB4X (Thymosin beta 4, X-linked)

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The Function of TMSB4X

Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase.

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Protein names

Recommended name:

Thymosin beta-4

Alternative name(s):

T beta-4
Fx
Seraspenide

TMSB4X SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS5979785 (TMSB4X) ??

Top Gene-Substance Interactions

TMSB4X Interacts with These Diseases

Disease Score

Substances That Increase TMSB4X

Substances Interaction Organism Category

Substances That Decrease TMSB4X

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • PPAR-gamma1
  • PPAR-gamma2
  • AP-1
  • c-Jun
  • NF-kappaB1
  • c-Fos

Tissue specificity:

Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.

Gene Pathways:

  • Regulation of actin cytoskeleton
  • Hemostasis

Induction:

By alpha interferons. Decreased levels in THP-1 cells after treatment with recombinant interferon-lambda.

Molecular Function:

  • Actin Monomer Binding
  • Poly(A) Rna Binding

Biological Processes:

  • Actin Cytoskeleton Organization
  • Actin Filament Organization
  • Platelet Degranulation
  • Sequestering Of Actin Monomers
  • Osteoblast Differentiation
  • Regulation Of Cell Migration
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| FX| AS28_08170| beta thymosin-like| fb08c07| fj40h03| H920_19324| N300_08947| N301_09291| N302_01165| N303_03183| N305_04105| N306_11933| N307_01658| N308_12569| N309_00650| N310_12540| N311_04469| N312_04816| N320_06011| N321_11659| N322_03777| N324_03180| N325_00164| N326_02262| N327_02338| N329_04739| N330_11956| N331_10722| N332_13865| N333_03362| N334_06750| N335_10418| N336_03335| N340_06692| N341_08739| PANDA_003054| prothymosin beta 4| prothymosin beta-4| Ptmb4| putative thymosin beta 4| Tb4| TB4X| Tbeta11| t beta 4| t beta-4| ThymB4X| thymosin b4| thymosin beta-11| Thymosin beta-12| thymosin, beta 4| Thymosin beta-4| thymosin beta 4-like| thymosin, beta 4 x| thymosin beta 4, X chromosome| thymosin, beta 4, X chromosome| tmsb4| tyb12| Y1Q_026152| Y956_05582| Z169_05809| zTB4| tmsb4x

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