• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. TMOD1

TMOD1 (Tropomodulin 1)

Loading...

The Function of TMOD1

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Tropomodulin-1

Alternative name(s):

Erythrocyte tropomodulin
E-Tmod

TMOD1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS139475366 (TMOD1) ??
  2. RS1475545 (TMOD1) ??

Top Gene-Substance Interactions

TMOD1 Interacts with These Diseases

Disease Score

Substances That Increase TMOD1

Substances Interaction Organism Category

Substances That Decrease TMOD1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Evi-1
  • CUTL1
  • MEF-2A
  • IRF-1
  • IRF-2

Tissue specificity:

Highly expressed in the erythrocyte, heart and skeletal muscle.

Gene Pathways:

  • Muscle contraction

Molecular Function:

  • Actin Binding
  • Tropomyosin Binding

Biological Processes:

  • Actin Filament Organization
  • Adult Locomotory Behavior
  • Lens Fiber Cell Development
  • Muscle Contraction
  • Muscle Filament Sliding
  • Myofibril Assembly
  • Pointed-End Actin Filament Capping
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Anapl_10791| CB1_001030012| D623_10019343| D9S57E| EGK_07519| Erythrocyte tropomodulin| E-Tmod| ETMOD| e-tropomodulin| GW7_18478| H920_19557| MDA_GLEAN10021555| N300_12744| N301_05668| N302_05692| N303_08322| N305_10143| N306_11759| N307_14483| N308_12160| N309_12929| N310_01984| N311_07236| N312_02889| N320_00161| N322_03150| N325_08668| N327_07088| N328_02748| N329_08138| N330_00128| N331_10677| N332_03841| N334_10786| N335_04243| N336_09406| N339_05607| N340_12786| N341_07750| PANDA_002926| Tmod| TREES_T100017573| Tropomodulin-1| UY3_05273| Y1Q_015718| Y956_08909| Z169_14773| tmod1

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved