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  3. TKT

TKT (Transketolase)

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The Function of TKT

Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.

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Protein names

Recommended name:

Transketolase

Short name:

TK

TKT SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS4687717 (TKT) ??

Top Gene-Substance Interactions

TKT Interacts with These Diseases

Disease Score

Substances That Increase TKT

Substances Interaction Organism Category

Substances That Decrease TKT

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p53
  • C/EBPalpha

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Disease
  • Pentose phosphate pathway

Cofactor:

Binds 1 thiamine pyrophosphate per subunit.

Molecular Function:

  • Cofactor Binding
  • Metal Ion Binding
  • Protein Homodimerization Activity
  • Transketolase Activity

Biological Processes:

  • Glyceraldehyde-3-Phosphate Biosynthetic Process
  • Pentose-Phosphate Shunt
  • Pentose-Phosphate Shunt, Non-Oxidative Branch
  • Regulation Of Growth
  • Xylulose Biosynthetic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| p68| A306_02325| Anapl_07219| AS27_11749| AS28_10147| D623_10011908| epididymis luminal protein 107| epididymis secretory protein Li 48| H920_13385| HEL107| HEL-S-48| M91_14521| M959_12287| MDA_GLEAN10016596| N300_10029| N301_13851| N302_10147| N303_08693| N305_08487| N306_12216| N307_07793| N308_01957| N320_03969| PAL_GLEAN10022207| PANDA_007559| SDDHD| TK| tkt1| transketolase-like protein| transketolase-like protein 2| transketolase (Wernicke-Korsakoff syndrome)| TREES_T100010302| Y1Q_000967| Y956_15231| Z169_04551| tkt

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