The Function of TKT
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
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Protein names
Recommended name:
TransketolaseShort name:
TK- RS4687717 (TKT) ??
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Top Gene-Substance Interactions
TKT Interacts with These Diseases
| Disease | Score |
Substances That Increase TKT
| Substances | Interaction | Organism | Category |
Substances That Decrease TKT
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Cofactor:
Binds 1 thiamine pyrophosphate per subunit.
Molecular Function:
Biological Processes:
- Glyceraldehyde-3-Phosphate Biosynthetic Process
- Pentose-Phosphate Shunt
- Pentose-Phosphate Shunt, Non-Oxidative Branch
- Regulation Of Growth
- Xylulose Biosynthetic Process