The Function of THRSP
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
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Protein names
Recommended name:
Thyroid hormone-inducible hepatic proteinShort name:
S14Alternative name(s):
Spot 14 proteinSPOT14
Top Gene-Substance Interactions
THRSP Interacts with These Diseases
| Disease | Score |
Substances That Increase THRSP
| Substances | Interaction | Organism | Category |
Substances That Decrease THRSP
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Mainly expressed in tissues that synthesize triglycerides.
Biological Processes:
- Transcription, Dna-Templated
- Regulation Of Transcription, Dna-Templated
- Lipid Metabolic Process
- Regulation Of Triglyceride Biosynthetic Process
- Regulation Of Lipid Biosynthetic Process