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  3. THRSP

THRSP (Thyroid hormone responsive)

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The Function of THRSP

Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.

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Protein names

Recommended name:

Thyroid hormone-inducible hepatic protein

Short name:

S14

Alternative name(s):

Spot 14 protein
SPOT14

Top Gene-Substance Interactions

THRSP Interacts with These Diseases

Disease Score

Substances That Increase THRSP

Substances Interaction Organism Category

Substances That Decrease THRSP

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • AP-1
  • c-Jun

Tissue specificity:

Mainly expressed in tissues that synthesize triglycerides.

Biological Processes:

  • Lipid Metabolic Process
  • Regulation Of Lipid Biosynthetic Process
  • Regulation Of Transcription, Dna-Templated
  • Regulation Of Triglyceride Biosynthetic Process
  • Transcription, Dna-Templated
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| thyroid hormone responsive protein| S14| AS28_07696| CB1_001567009| H920_09215| lipogenic protein 1| Lipogenic protein S14| Lpgp| LPGP1| M91_05402| M959_03830| MDA_GLEAN10004313| Mid1-interacting protein 1| Mid1-interacting protein 1A| Mid1-interacting protein 1-B| N303_02071| N307_00179| N320_11523| N322_08137| N324_10326| N336_03062| PAL_GLEAN10025538| PANDA_004379| SPOT14| SPOT14 homolog| spot 14 protein| THRP| THRSPA| thyroid hormone-inducible hepatic protein| thyroid hormone-inducible hepatic protein-like protein| thyroid hormone-responsive protein| thyroid hormone responsive SPOT14| thyroid hormone responsive spot 14 alpha| thyroid hormone responsive SPOT14 homolog| thyroid hormone responsive (SPOT14 homolog, rat)| TREES_T100007977| uncharacterized protein LOC568167| Y956_06633| Z169_07736| thrsp

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