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  3. TAGLN

TAGLN (Transgelin)

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The Function of TAGLN

Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.

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Protein names

Recommended name:

Transgelin

Alternative name(s):

22 kDa actin-binding protein
Protein WS3-10
Smooth muscle protein 22-alpha
SM22-alpha

TAGLN SNPs

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  1. RS508487 (TAGLN) ??

Top Gene-Substance Interactions

Substances That Increase TAGLN

Substances Interaction Organism Category

Substances That Decrease TAGLN

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Egr-1
  • Nkx2-5
  • Sp1
  • c-Fos

Induction:

Overexpressed in senescent human fibroblasts.

Biological Processes:

  • Epithelial Cell Differentiation
  • Muscle Organ Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 22 kDa actin-binding protein| 25 kDa F-actin-binding protein| actin-associated protein p27| CB1_000200063| EGK_06932| GW7_18643| H920_07533| M91_21347| M959_01861| MDA_GLEAN10018948| N300_01373| N302_11172| N303_12983| N307_03580| PAL_GLEAN10009066| PANDA_008172| putative transgelin| Sm22| SM22A| Sm22alpha| SM22-alpha| sm22alpha-b| smcc| smooth muscle 22 protein| smooth muscle protein 22-alpha| TAGL| tagln1| transgelin variant 2| UY3_07692| Ws310| WS3-10| tagln

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