The Function of TAGLN
Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.
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Protein names
Recommended name:
TransgelinAlternative name(s):
22 kDa actin-binding proteinProtein WS3-10
Smooth muscle protein 22-alpha
SM22-alpha
- RS508487 (TAGLN) ??
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Top Gene-Substance Interactions
Substances That Increase TAGLN
| Substances | Interaction | Organism | Category |
Substances That Decrease TAGLN
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Induction:
Overexpressed in senescent human fibroblasts.