The Function of TAC1
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
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Protein names
Recommended name:
Protachykinin-1Short name:
PPTAlternative name(s):
NKANeuromedin L
Substance K
NPK
- RS10255878 (TAC1) ??
- RS10486003 (TAC1) ??
- RS1229542 (TAC1) ??
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Top Gene-Substance Interactions
TAC1 Interacts with These Diseases
| Disease | Score |
Substances That Increase TAC1
| Substances | Interaction | Organism | Category |
Substances That Decrease TAC1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Antibacterial Humoral Response
- Antifungal Humoral Response
- Associative Learning
- Cell-Cell Signaling
- Cellular Response To Nerve Growth Factor Stimulus
- Chemical Synaptic Transmission
- Defense Response To Gram-Negative Bacterium
- Defense Response To Gram-Positive Bacterium
- Detection Of Abiotic Stimulus
- Inflammatory Response
- Innate Immune Response
- Insemination
- Long-Term Memory
- Negative Regulation Of Heart Rate
- Neuropeptide Signaling Pathway
- Positive Regulation Of Action Potential
- Positive Regulation Of Acute Inflammatory Response
- Positive Regulation Of Corticosterone Secretion
- Positive Regulation Of Cytosolic Calcium Ion Concentration
- Positive Regulation Of Epithelial Cell Migration
- Positive Regulation Of Lymphocyte Proliferation
- Positive Regulation Of Ossification
- Positive Regulation Of Renal Sodium Excretion
- Positive Regulation Of Saliva Secretion
- Positive Regulation Of Stress Fiber Assembly
- Positive Regulation Of Synaptic Transmission, Cholinergic
- Positive Regulation Of Synaptic Transmission, Gabaergic
- Regulation Of Blood Pressure
- Response To Hormone
- Response To Lipopolysaccharide
- Response To Morphine
- Response To Pain
- Response To Yeast
- Sensory Perception Of Pain
- Tachykinin Receptor Signaling Pathway