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  3. SUCLG2

SUCLG2 (Succinate-CoA ligase GDP-forming beta subunit)

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The Function of SUCLG2

Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA.

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Protein names

Recommended name:

Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

Short name:

G-SCS

Alternative name(s):

GTP-specific succinyl-CoA synthetase subunit beta
GTPSCS
Succinyl-CoA synthetase beta-G chain
SCS-betaG

SUCLG2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS17806888 (SUCLG2) ??
  2. RS2363709 (SUCLG2) ??
  3. RS4453858 (SUCLG2) ??
  4. RS62256378 (SUCLG2) ??
  5. RS6792584 (SUCLG2) ??
  6. RS76010824 (SUCLG2) ??
  7. RS977102 (SUCLG2) ??

Top Gene-Substance Interactions

SUCLG2 Interacts with These Diseases

Disease Score

Substances That Increase SUCLG2

Substances Interaction Organism Category

Substances That Decrease SUCLG2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

Tissue specificity:

Mainly expressed in liver, kidney, heart, spleen and skeletal muscle. Also found in intestine and colon, and in low amounts in lung, brain, prostate, testis and ovary.

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Citrate cycle (TCA cycle)
  • Propanoate metabolism

Molecular Function:

  • Atp Binding
  • Gdp Binding
  • Gtp Binding
  • Succinate-Coa Ligase (Gdp-Forming) Activity

Biological Processes:

  • Succinate Metabolic Process
  • Succinyl-Coa Metabolic Process
  • Tricarboxylic Acid Cycle

Drug Bank:

  • Succinic Acid
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| SCS| A306_04901| AF171077| Anapl_03603| AS27_11623| AS28_13289| CB1_001712001| D623_10022761| D6Wsu120e| fd44e06| gbeta| GTP-specific succinyl-CoA synthetase beta subunit| GTP-specific succinyl-CoA synthetase subunit beta| H920_16677| I79_000350| M959_05649| MDA_GLEAN10017378| N300_07184| N301_08162| N302_15808| N303_08592| N305_08532| N306_07185| N307_14206| N308_01289| N310_01891| N311_00666| N312_09234| N320_12893| N321_02754| N322_01469| N325_02005| N326_12948| N327_00794| N328_05121| N329_07398| N330_00712| N331_00985| N332_12706| N333_12870| N334_13055| N335_01326| N339_04228| N340_13181| N341_05015| PAL_GLEAN10022135| PANDA_020149| SCS-betaG| succinate-CoA ligase, GDP-forming, beta subunit| succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial| succinate-Coenzyme A ligase, GDP-forming, beta subunit| succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial| Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial| succinyl-CoA ligase (GDP-forming) subunit beta, mitochondrial| succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial| succinyl-CoA synthetase, beta-G chain| Succinyl-CoA synthetase beta-G chain| succinyl-CoA synthetase beta-subunit| SUCLGb| TREES_T100015281| Y1Q_014892| Y956_14402| Z169_16114| suclg2

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