The Function of ST6GAL1
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.
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Protein names
Recommended name:
Beta-galactoside alpha-2,6-sialyltransferase 1Alternative name(s):
Alpha 2,6-ST 1B-cell antigen CD75
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1
ST6Gal I
ST6GalI
Sialyltransferase 1
- RS10937275 (ST6GAL1) ??
- RS11710456 (ST6GAL1) ??
- RS16861329 (ST6GAL1) ??
- RS17776120 (ST6GAL1) ??
- RS2239612 (ST6GAL1) ??
- RS3821819 (ST6GAL1) ??
- RS6778436 (ST6GAL1) ??
- RS7634389 (ST6GAL1) ??
- RS7652995 (ST6GAL1) ??
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Top Gene-Substance Interactions
ST6GAL1 Interacts with These Diseases
| Disease | Score |
Substances That Increase ST6GAL1
| Substances | Interaction | Organism | Category |
Substances That Decrease ST6GAL1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Enzyme Regulation:
Inhibited by CTP.
Molecular Function:
Biological Processes:
- N-Acetylneuraminate Metabolic Process
- Humoral Immune Response
- Oligosaccharide Metabolic Process
- O-Glycan Processing
- Protein N-Linked Glycosylation Via Asparagine
- Positive Regulation Of Mononuclear Cell Proliferation
- Response To Ethanol
- Negative Regulation Of Chemotaxis
- Sialylation
- Regulation Of Substrate Adhesion-Dependent Cell Spreading
- Protein Sialylation
- Negative Regulation Of Macrophage Apoptotic Process