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  3. ST6GAL1

ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1)

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The Function of ST6GAL1

Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Beta-galactoside alpha-2,6-sialyltransferase 1

Alternative name(s):

Alpha 2,6-ST 1
B-cell antigen CD75
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1
ST6Gal I
ST6GalI
Sialyltransferase 1

ST6GAL1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10937275 (ST6GAL1) ??
  2. RS11710456 (ST6GAL1) ??
  3. RS16861329 (ST6GAL1) ??
  4. RS17776120 (ST6GAL1) ??
  5. RS2239612 (ST6GAL1) ??
  6. RS3821819 (ST6GAL1) ??
  7. RS6778436 (ST6GAL1) ??
  8. RS7634389 (ST6GAL1) ??
  9. RS7652995 (ST6GAL1) ??

Top Gene-Substance Interactions

ST6GAL1 Interacts with These Diseases

Disease Score

Substances That Increase ST6GAL1

Substances Interaction Organism Category

Substances That Decrease ST6GAL1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GR
  • GR-alpha
  • GR-beta
  • TBP
  • TFIID

Gene Pathways:

  • Metabolic pathways
  • Metabolism of proteins
  • N-Glycan biosynthesis
  • Other types of O-glycan biosynthesis

Enzyme Regulation:

Inhibited by CTP.

Molecular Function:

  • Beta-Galactoside Alpha-2,6-Sialyltransferase Activity
  • Sialyltransferase Activity

Biological Processes:

  • Humoral Immune Response
  • N-Acetylneuraminate Metabolic Process
  • O-Glycan Processing
  • Oligosaccharide Metabolic Process
  • Protein N-Linked Glycosylation Via Asparagine
  • Sialylation
  • Negative Regulation Of Chemotaxis
  • Negative Regulation Of Macrophage Apoptotic Process
  • Positive Regulation Of Mononuclear Cell Proliferation
  • Protein Sialylation
  • Regulation Of Substrate Adhesion-Dependent Cell Spreading
  • Response To Ethanol
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| alpha-2,6-sialyltransferase| alpha 2,6 sialyltransferase I| alpha 2,6-ST 1| Anapl_14765| AS27_09866| AS28_14422| B-cell antigen CD75| beta-galactosamide alpha-2,6-sialyltranferase 1| beta-galactosamide alpha-2,6-sialyltransferase I| beta-galactoside alpha-2,6-sialyltransferase| beta galactoside alpha 2,6 sialyltransferase 1| Beta-galactoside alpha-2,6-sialyltransferase 1| beta-galactoside alpha 2,6-sialyltransferase ST6Gal I| CB1_001118019| CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1| D623_10016114| EGK_12196| Gal beta 1,4 GlcNAc alpha 2,6-sialyltransferase| GW7_17196| H920_05360| I79_016087| M91_05085| M959_05043| MDA_GLEAN10014140| N300_10427| N301_13925| N302_05997| N303_09997| N305_12977| N306_07686| N307_06224| N308_10898| N309_06226| N310_02749| N311_11753| N321_04699| N322_11481| N324_04298| N327_03095| N328_02472| N329_02832| N330_01251| N331_08782| N333_00551| N334_02411| N339_01672| N340_01805| N341_02548| PAL_GLEAN10018227| PANDA_002792| sialyltransferase 1| sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase)| Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase)| Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase)| siat1| ST6 beta-galactosamide alpha-2,6-sialyltranferase 1| ST6 beta-galactosamide alpha-2,6-sialyltransferase 1| St6gal| St6galI| St6 Gal I| St6Gal-I| ST6Gal I| ST6N| ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1| Y1Q_019080| Y956_01623| Z169_02932| st6gal1

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