The Function of SPTBN2
Probably plays an important role in neuronal membrane skeleton.
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Protein names
Recommended name:
Spectrin beta chain, non-erythrocytic 2Alternative name(s):
Beta-III spectrinSpinocerebellar ataxia 5 protein
Top Gene-Substance Interactions
Substances That Increase SPTBN2
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Substances That Decrease SPTBN2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Highly expressed in brain, kidney, pancreas, and liver, and at lower levels in lung and placenta.
Gene Pathways:
Molecular Function:
- Actin Binding
- Ras Guanyl-Nucleotide Exchange Factor Activity
- Structural Constituent Of Cytoskeleton
- Phospholipid Binding
- Cadherin Binding Involved In Cell-Cell Adhesion
Biological Processes:
- Mapk Cascade
- Er To Golgi Vesicle-Mediated Transport
- Axon Guidance
- Synapse Assembly
- Vesicle-Mediated Transport
- Antigen Processing And Presentation Of Exogenous Peptide Antigen Via Mhc Class Ii
- Cerebellar Purkinje Cell Layer Morphogenesis
- Adult Behavior
- Multicellular Organism Growth
- Actin Filament Capping
- Cellular Response To Ethanol