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  3. SPRR3

SPRR3 (Small proline rich protein 3)

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The Function of SPRR3

Cross-linked envelope protein of keratinocytes.

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Protein names

Recommended name:

Small proline-rich protein 3

Alternative name(s):

22 kDa pancornulin
Cornifin beta
Esophagin

Top Gene-Substance Interactions

Substances That Increase SPRR3

Substances Interaction Organism Category

Substances That Decrease SPRR3

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • c-Jun
  • MRF-2
  • c-Fos
  • Bach1
  • Brachyury
  • Pax-2
  • Bach2
  • c-Myb

Induction:

During squamous differentiation of epidermal keratinocytes.

Molecular Function:

  • Structural Molecule Activity

Biological Processes:

  • Epidermis Development
  • Keratinization
  • Keratinocyte Differentiation
  • Peptide Cross-Linking
  • Wound Healing
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

small proline-rich protein 1A| 22 kDa pancornulin| cornifin beta| esophagin| H920_13654| small proline-rich protein 3| SPR3| SPRR1A| sprr3

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