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  3. SOX6

SOX6 (SRY-box 6)

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The Function of SOX6

Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.

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Protein names

Recommended name:

Transcription factor SOX-6

SOX6 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1401454 (SOX6) ??
  2. RS16932455 (SOX6) ??
  3. RS2028162 (SOX6) ??
  4. RS297325 (SOX6) ??
  5. RS4756846 (SOX6) ??
  6. RS4757391 (SOX6) ??
  7. RS7117858 (SOX6) ??

Top Gene-Substance Interactions

Substances That Increase SOX6

Substances Interaction Organism Category

Substances That Decrease SOX6

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • C/EBPbeta
  • C/EBPalpha
  • p300

Tissue specificity:

Expressed in a wide variety of tissues, most abundantly in skeletal muscle.

Molecular Function:

  • Dna Binding
  • Sequence-Specific Dna Binding
  • Transcription Factor Activity, Sequence-Specific Dna Binding
  • Transcription Regulatory Region Dna Binding

Biological Processes:

  • Astrocyte Differentiation
  • Cardiac Muscle Cell Differentiation
  • Cartilage Development
  • Cell Morphogenesis
  • Cellular Response To Transforming Growth Factor Beta Stimulus
  • Erythrocyte Development
  • Gene Silencing
  • In Utero Embryonic Development
  • Muscle Organ Development
  • Negative Regulation Of Cardiac Muscle Cell Differentiation
  • Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Oligodendrocyte Cell Fate Specification
  • Positive Regulation Of Cartilage Development
  • Positive Regulation Of Chondrocyte Differentiation
  • Positive Regulation Of Mesenchymal Stem Cell Differentiation
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Post-Embryonic Development
  • Regulation Of Transcription, Dna-Templated
  • Transcription, Dna-Templated
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| SRY (sex determining region Y)-box 5| SRY (sex determining region Y)-box 5 isoform a isoform 3-like protein| A306_03103| AS27_14497| AS28_03467| CB1_056579133| fc35a10| fc50e03| GW7_14874| H920_19893| hssox6| I79_011918| M91_10989| M959_15060| MDA_GLEAN10023797| N300_06522| N301_04027| N302_13670| N303_00133| N306_09641| N307_13513| N308_07898| N310_13145| N311_10349| N320_00856| N321_12438| N322_12992| N325_03096| N326_12870| N328_03367| N330_01575| N331_07828| N334_12155| N335_05701| N336_12713| N339_01859| N340_03159| PAL_GLEAN10004343| PANDA_009287| SOX5| Sox-6| sox6b| SOXD| sox-lz| SRY box 6| SRY-box containing gene 6| SRY (sex determining region Y)-box 6| transcription factor Sox-6| transcription factor SOX-6-like| transcription factor SOX-6-like protein| TREES_T100011585| UY3_04485| XELAEV_18024631mg| xSox6| Y1Q_014583| Y956_06777| Z169_01629| sox6

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