The Function of SOX6
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.
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Protein names
Recommended name:
Transcription factor SOX-6- RS1401454 (SOX6) ??
- RS16932455 (SOX6) ??
- RS2028162 (SOX6) ??
- RS297325 (SOX6) ??
- RS4756846 (SOX6) ??
- RS4757391 (SOX6) ??
- RS7117858 (SOX6) ??
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Top Gene-Substance Interactions
Substances That Increase SOX6
| Substances | Interaction | Organism | Category |
Substances That Decrease SOX6
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in a wide variety of tissues, most abundantly in skeletal muscle.
Molecular Function:
- Dna Binding
- Transcription Factor Activity, Sequence-Specific Dna Binding
- Sequence-Specific Dna Binding
- Transcription Regulatory Region Dna Binding
Biological Processes:
- Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
- Cell Morphogenesis
- In Utero Embryonic Development
- Transcription, Dna-Templated
- Regulation Of Transcription, Dna-Templated
- Muscle Organ Development
- Post-Embryonic Development
- Gene Silencing
- Oligodendrocyte Cell Fate Specification
- Positive Regulation Of Chondrocyte Differentiation
- Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
- Astrocyte Differentiation
- Erythrocyte Development
- Cartilage Development
- Cardiac Muscle Cell Differentiation
- Positive Regulation Of Cartilage Development
- Cellular Response To Transforming Growth Factor Beta Stimulus
- Negative Regulation Of Cardiac Muscle Cell Differentiation
- Positive Regulation Of Mesenchymal Stem Cell Differentiation