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  3. SOX11

SOX11 (SRY-box 11)

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The Function of SOX11

Transcriptional factor involved in the embryonic neurogenesis. May also have a role in tissue modeling during development.

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Protein names

Recommended name:

Transcription factor SOX-11

SOX11 SNPs

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  1. RS16864170 (SOX11) ??

Top Gene-Substance Interactions

SOX11 Interacts with These Diseases

Disease Score

Substances That Increase SOX11

Substances Interaction Organism Category

Substances That Decrease SOX11

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • NF-kappaB1

Tissue specificity:

Expressed mainly in the nervous system, brain (fetus and adult) and hear (adult).

Molecular Function:

  • Enhancer Sequence-Specific Dna Binding
  • Rna Polymerase Ii Core Promoter Sequence-Specific Dna Binding
  • Rna Polymerase Ii Transcription Coactivator Activity
  • Transcriptional Activator Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
  • Transcription Factor Activity, Sequence-Specific Dna Binding
  • Transcription Regulatory Region Sequence-Specific Dna Binding
  • Translation Factor Activity, Rna Binding

Biological Processes:

  • Cardiac Ventricle Formation
  • Closure Of Optic Fissure
  • Cornea Development In Camera-Type Eye
  • Embryonic Digestive Tract Morphogenesis
  • Embryonic Skeletal System Morphogenesis
  • Eyelid Development In Camera-Type Eye
  • Glial Cell Development
  • Glial Cell Proliferation
  • Hard Palate Development
  • Kidney Development
  • Lens Morphogenesis In Camera-Type Eye
  • Limb Bud Formation
  • Lung Morphogenesis
  • Negative Regulation Of Cell Death
  • Negative Regulation Of Gene Expression
  • Negative Regulation Of Glial Cell Proliferation
  • Negative Regulation Of Lymphocyte Proliferation
  • Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Negative Regulation Of Transcription Regulatory Region Dna Binding
  • Neural Crest Cell Development
  • Neural Tube Formation
  • Neuroepithelial Cell Differentiation
  • Neuron Differentiation
  • Noradrenergic Neuron Differentiation
  • Oligodendrocyte Development
  • Outflow Tract Morphogenesis
  • Positive Regulation Of Bmp Signaling Pathway
  • Positive Regulation Of Cell Proliferation
  • Positive Regulation Of Gene Expression
  • Positive Regulation Of Hippo Signaling
  • Positive Regulation Of Hormone Secretion
  • Positive Regulation Of Lens Epithelial Cell Proliferation
  • Positive Regulation Of Neurogenesis
  • Positive Regulation Of Neuron Differentiation
  • Positive Regulation Of Ossification
  • Positive Regulation Of Osteoblast Differentiation
  • Positive Regulation Of Stem Cell Proliferation
  • Positive Regulation Of Transcription, Dna-Templated
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
  • Signal Transduction Involved In Cell Cycle Checkpoint
  • Skeletal Muscle Cell Differentiation
  • Skeletal System Development
  • Soft Palate Development
  • Somite Development
  • Spinal Cord Development
  • Sympathetic Nervous System Development
  • Ventricular Septum Morphogenesis
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Anapl_12845| AS27_15694| AS28_03609| CB1_001616022| cSox11| end1| H920_04669| M959_14803| MRD27| N300_07681| N302_01856| N305_01635| N307_03587| N308_11048| N309_13814| N325_04648| PAL_GLEAN10020090| sox11-a| SOX11a| sox11-b| Sox11 transcription factor| SRY box 11| SRY-box containing gene 11| SRY-box containing gene 11a| SRY-box containing protein 11| SRY-box containing protein 11a| SRY-box containing transcription factor 11a| SRY-related HMG-box gene 11| SRY (sex determining region Y)-box 11| SRY (sex-determining region Y)-box 11| transcription factor Sox11| transcription factor Sox-11| TREES_T100010048| UY3_00741| XLS13| xls13a| XLS13b| xsox11| xSOX-11| Y1Q_010374| Y956_06025| Z169_13770| sox11

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