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  3. SNRPD3

SNRPD3 (Small nuclear ribonucleoprotein D3 polypeptide)

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The Function of SNRPD3

Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.

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Protein names

Recommended name:

Small nuclear ribonucleoprotein Sm D3

Alternative name(s):

Sm-D3
snRNP core protein D3

Top Gene-Substance Interactions

SNRPD3 Interacts with These Diseases

Disease Score

Substances That Increase SNRPD3

Substances Interaction Organism Category

Substances That Decrease SNRPD3

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • CUTL1
  • YY1

Gene Pathways:

  • Gene Expression
  • Metabolism of RNA
  • Post-Elongation Processing of the Transcript
  • Transcription
  • Systemic lupus erythematosus

Molecular Function:

  • Enzyme Binding
  • Histone Pre-Mrna Dcp Binding
  • Poly(A) Rna Binding
  • Telomerase Rna Binding
  • U1 Snrnp Binding
  • U2 Snrna Binding
  • U7 Snrna Binding

Biological Processes:

  • Histone Mrna Metabolic Process
  • Mrna Splicing, Via Spliceosome
  • Nuclear Import
  • Protein Methylation
  • Rna Splicing
  • Spliceosomal Complex Assembly
  • Spliceosomal Snrnp Assembly
  • Termination Of Rna Polymerase Ii Transcription
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| AS27_08981| AS28_08507| CB1_000302038| EGK_02876| EH28_22174| H920_14909| M91_17217| M959_05953| MDA_GLEAN10012780| N300_08229| N301_16783| N302_15502| N303_08768| N307_14096| N308_10017| N310_13579| N311_07785| N312_04946| N320_05961| N322_02423| N324_02538| N325_10116| N326_07451| N327_01699| N329_10085| N330_04347| N331_07001| N333_11372| N334_00653| N335_11523| N336_10352| N340_04173| N341_09736| PANDA_014546| small nuclear ribonucleoprotein D3| small nuclear ribonucleoprotein D3 polypeptide 18kDa| small nuclear ribonucleoprotein polypeptide D3| Small nuclear ribonucleoprotein Sm D3| small nuclear ribonucleoprotein Sm D3-like protein| sm-D3| SMD3| snRNP core protein D3| TREES_T100005557| Y1Q_004157| Y956_15739| Z169_10708| snrpd3

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