The Function of SLIT3
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
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Protein names
Recommended name:
Slit homolog 3 proteinAlternative name(s):
Slit-3Multiple epidermal growth factor-like domains protein 5
Multiple EGF-like domains protein 5
- RS12188351 (SLIT3) ??
- RS2974438 (SLIT3) ??
- RS4282339 (SLIT3) ??
- RS6555855 (SLIT3) ??
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Top Gene-Substance Interactions
Substances That Increase SLIT3
| Substances | Interaction | Organism | Category |
Substances That Decrease SLIT3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Predominantly expressed in thyroid.
Gene Pathways:
Molecular Function:
Biological Processes:
- Animal Organ Morphogenesis
- Apoptotic Process Involved In Luteolysis
- Axon Extension Involved In Axon Guidance
- Axon Guidance
- Cellular Response To Hormone Stimulus
- Negative Chemotaxis
- Negative Regulation Of Cell Growth
- Negative Regulation Of Cell Proliferation
- Negative Regulation Of Chemokine-Mediated Signaling Pathway
- Negative Regulation Of Gene Expression
- Regulation Of Axonogenesis
- Response To Cortisol
- Roundabout Signaling Pathway