Summary of SLC39A6
The gene codes for a protein, solute carrier family 39 member 6. It is a zinc transporter [R].
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The Function of SLC39A6
May act as a zinc-influx transporter.
Protein names
Recommended name:
Zinc transporter ZIP6Short name:
ZIP-6Alternative name(s):
Estrogen-regulated protein LIV-1Solute carrier family 39 member 6
Zrt- and Irt-like protein 6
- RS1050631 (SLC39A6) ??
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Top Gene-Substance Interactions
SLC39A6 Interacts with These Diseases
| Disease | Score |
Substances That Increase SLC39A6
| Substances | Interaction | Organism | Category |
Substances That Decrease SLC39A6
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma.
Gene Pathways:
Induction:
Up-regulated by estrogen in breast cancer cells lines.