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  3. SLC39A6

SLC39A6 (Solute carrier family 39 member 6)

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Summary of SLC39A6

The gene codes for a protein, solute carrier family 39 member 6. It is a zinc transporter [R].

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The Function of SLC39A6

May act as a zinc-influx transporter.

Protein names

Recommended name:

Zinc transporter ZIP6

Short name:

ZIP-6

Alternative name(s):

Estrogen-regulated protein LIV-1
Solute carrier family 39 member 6
Zrt- and Irt-like protein 6

SLC39A6 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1050631 (SLC39A6) ??

Top Gene-Substance Interactions

SLC39A6 Interacts with These Diseases

Disease Score

Substances That Increase SLC39A6

Substances Interaction Organism Category

Substances That Decrease SLC39A6

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • STAT3
  • XBP-1

Tissue specificity:

Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma.

Gene Pathways:

  • Transmembrane transport of small molecules

Induction:

Up-regulated by estrogen in breast cancer cells lines.

Molecular Function:

  • Zinc Ion Transmembrane Transporter Activity

Biological Processes:

  • Cellular Zinc Ion Homeostasis
  • Zinc Ii Ion Transmembrane Import
  • Zinc Ii Ion Transmembrane Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_10060| Anapl_14182| AS27_15892| AS28_02266| D623_10021219| endoplasmic reticulum membrane-linked protein| endoplasmic reticulum membrane protein| Ermelin| estrogen-regulated LIV-1 protein| estrogen-regulated protein LIV-1| GW7_04828| H920_11201| I79_007114| liv1| LIV-1| LIV-1 protein, estrogen regulated| M959_14226| MDA_GLEAN10021371| N300_10515| N301_04546| N302_10345| N303_02469| N305_08016| N306_08339| N307_15472| N308_06080| N309_13007| N310_05326| N311_02554| N320_07222| N321_00339| N322_02583| N325_07879| N326_08667| N327_11530| N328_08372| N329_11743| N331_10391| N332_12333| N333_01473| N335_01282| N336_01892| N339_10644| N340_12243| N341_02027| PAL_GLEAN10023107| PANDA_014101| solute carrier family 39 , member 6| solute carrier family 39 (metal ion transporter), member 6| solute carrier family 39 (zinc transporter), member 6| solute carrier family 39 (zinc transporter), member 6 tv1| TREES_T100018591| UY3_08923| Y1Q_012302| Y956_00742| Z169_15968| Zinc transporter ZIP6| ZIP6| ZIP-6| zrt- and Irt-like protein 6| slc39a6

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