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  3. SLC39A1

SLC39A1 (Solute carrier family 39 member 1)

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The Function of SLC39A1

Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.

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Protein names

Recommended name:

Zinc transporter ZIP1

Short name:

ZIP-1

Alternative name(s):

Solute carrier family 39 member 1
Zinc-iron-regulated transporter-like
Zrt- and Irt-like protein 1
hZIP1

SLC39A1 SNPs

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  1. RS11264736 (SLC39A1) ??

Top Gene-Substance Interactions

SLC39A1 Interacts with These Diseases

Disease Score

Substances That Increase SLC39A1

Substances Interaction Organism Category

Substances That Decrease SLC39A1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • NF-kappaB1

Tissue specificity:

Ubiquitous. Expressed in most adult and fetal tissues including the epidermis.

Gene Pathways:

  • Transmembrane transport of small molecules

Molecular Function:

  • Inorganic Cation Transmembrane Transporter Activity
  • Zinc Ion Transmembrane Transporter Activity

Biological Processes:

  • Cation Transport
  • Embryonic Cranial Skeleton Morphogenesis
  • In Utero Embryonic Development
  • Limb Development
  • Zinc Ii Ion Transmembrane Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CB1_000306061| DrZIP1| frzip1p| M91_03042| mZIP1| PAL_GLEAN10005475| PANDA_011547| solute carrier family 39 , member 1| solute carrier family 39 (zinc transporter), member 1| solute carrier family 39 (zinc transporter), member 3| TREES_T100021939| UY3_14685| Y1Q_000266| zinc transporter ZIP1| zinc transporter ZIP1-like protein| ZIP1| ZIP-1| ZIP zinc uptake transporter 1| Zirtl| zrt- and Irt-like protein 1| Zrt/Irt-like protein 1| slc39a1

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