The Function of SLC35D1
Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.
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Protein names
Recommended name:
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporterAlternative name(s):
UDP-GlcA/UDP-GalNAc transporterSolute carrier family 35 member D1
UDP-galactose transporter-related protein 7
UGTrel7
Top Gene-Substance Interactions
SLC35D1 Interacts with These Diseases
| Disease | Score |
Substances That Increase SLC35D1
| Substances | Interaction | Organism | Category |
Substances That Decrease SLC35D1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Ubiquitous.
Gene Pathways:
Molecular Function:
- Udp-Glucuronic Acid Transmembrane Transporter Activity
- Pyrimidine Nucleotide-Sugar Transmembrane Transporter Activity
Biological Processes:
- Udp-Glucuronate Biosynthetic Process
- Carbohydrate Transport
- Chondroitin Sulfate Biosynthetic Process
- Embryonic Skeletal System Development