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  3. SLC35D1

SLC35D1 (Solute carrier family 35 member D1)

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The Function of SLC35D1

Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.

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Protein names

Recommended name:

UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter

Alternative name(s):

UDP-GlcA/UDP-GalNAc transporter
Solute carrier family 35 member D1
UDP-galactose transporter-related protein 7
UGTrel7

Top Gene-Substance Interactions

SLC35D1 Interacts with These Diseases

Disease Score

Substances That Increase SLC35D1

Substances Interaction Organism Category

Substances That Decrease SLC35D1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Evi-1
  • CREB
  • deltaCREB
  • FOXF2
  • Nkx5-1
  • GATA-2

Tissue specificity:

Ubiquitous.

Gene Pathways:

  • Metabolism
  • Transmembrane transport of small molecules

Molecular Function:

  • Pyrimidine Nucleotide-Sugar Transmembrane Transporter Activity
  • Udp-Glucuronic Acid Transmembrane Transporter Activity

Biological Processes:

  • Carbohydrate Transport
  • Udp-Glucuronate Biosynthetic Process
  • Chondroitin Sulfate Biosynthetic Process
  • Embryonic Skeletal System Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_13596| AS27_08227| AS28_09843| C330011J09| CB1_001435010| D623_10021909| EH28_13024| M91_12796| M959_05747| MDA_GLEAN10008660| N300_00654| N301_10335| N302_07536| N303_09451| N305_09484| N307_10782| N308_08011| N309_08352| N311_11784| N320_05059| N322_03418| N324_07901| N326_04342| N332_04327| N333_07768| PAL_GLEAN10023845| PANDA_010916| SLC35D2| solute carrier family 35 , member D1| solute carrier family 35 member D2| solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1| solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1| TREES_T100002438| UDP-galactose transporter-related 7| UDP-galactose transporter-related protein 7| UDP-GlcA/UDP-GalNAc transporter| UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter| UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter| UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter-like| UGTREL7| Y1Q_020165| Y956_08791| Z169_03004| slc35d1

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