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  3. SLC24A3

SLC24A3 (Solute carrier family 24 member 3)

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Summary of SLC24A3

The gene codes for a protein, solute carrier family 24 member 3. It aids with intracellular calcium homeostasis and electrical conduction [R].

0 users want this gene increased, 0 users want it decreased

The Function of SLC24A3

Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).

Protein names

Recommended name:

Sodium/potassium/calcium exchanger 3

Short name:

+

Alternative name(s):

Na(+
2+
Solute carrier family 24 member 3

SLC24A3 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2424234 (SLC24A3) ??
  2. RS3790268 (SLC24A3) ??
  3. RS6081541 (SLC24A3) ??
  4. RS6136813 (SLC24A3) ??

Top Gene-Substance Interactions

Substances That Increase SLC24A3

Substances Interaction Organism Category

Substances That Decrease SLC24A3

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • Evi-1
  • RORalpha2
  • NF-kappaB1
  • PPAR-alpha
  • MRF-2
  • NF-kappaB2
  • RelA

Tissue specificity:

Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.

Gene Pathways:

  • Transmembrane transport of small molecules

Molecular Function:

  • Calcium, Potassium:Sodium Antiporter Activity
  • Calcium Channel Activity
  • Calcium Ion Binding
  • Potassium Ion Binding
  • Sodium Ion Binding
  • Symporter Activity

Biological Processes:

  • Cellular Calcium Ion Homeostasis
  • Ion Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| solute carrier family 24 (sodium/potassium/calcium exchanger), m| Anapl_14767| AS27_04152| AS28_04360| CB1_000637001| D623_10009723| H920_09574| I79_001860| M91_21318| M959_00717| N300_10193| N301_10932| N302_02497| N303_00712| N306_14491| N307_07006| N308_05789| N309_01687| N310_11150| N311_10515| N312_07835| N320_00857| N321_07453| N322_05197| N324_07231| N325_07951| N327_06528| N328_08424| N330_02484| N331_12935| N332_01124| N333_13531| N334_09218| N335_07748| N336_04209| N339_06744| N340_09541| Na(+)/K(+)/Ca(2+)-exchange protein 3| Nckx3| PAL_GLEAN10024019| PANDA_008312| potassium-dependent sodium-calcium exchanger NCKX3 (SLC24A3)| slc24a4| sodium calcium exchanger| sodium/potassium/calcium exchanger 3| sodium/potassium/calcium exchanger 3-like protein| solute carrier family 24 , member 3| solute carrier family 24 (sodium/potassium/calcium exchanger), member 3| solute carrier family 24 (sodium/potassium/calcium exchanger), member 4| TREES_T100008125| UY3_10210| Y1Q_001152| Y956_14477| Z169_03921| slc24a3

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