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  3. SERPINH1

SERPINH1 (Serpin family H member 1)

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The Function of SERPINH1

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

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Protein names

Recommended name:

Serpin H1

Alternative name(s):

47 kDa heat shock protein
Arsenic-transactivated protein 3
AsTP3
Cell proliferation-inducing gene 14 protein
Collagen-binding protein
Colligin
Rheumatoid arthritis-related antigen RA-A47

SERPINH1 SNPs

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  1. RS606452 (SERPINH1) ??
  2. RS606460 (SERPINH1) ??
  3. RS634552 (SERPINH1) ??

Top Gene-Substance Interactions

SERPINH1 Interacts with These Diseases

Disease Score

Substances That Increase SERPINH1

Substances Interaction Organism Category

Substances That Decrease SERPINH1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p53

Gene Pathways:

  • Extracellular matrix organization

Induction:

By heat shock.

Molecular Function:

  • Collagen Binding
  • Poly(A) Rna Binding
  • Serine-Type Endopeptidase Inhibitor Activity

Biological Processes:

  • Chondrocyte Development Involved In Endochondral Bone Morphogenesis
  • Collagen Biosynthetic Process
  • Collagen Fibril Organization
  • Protein Maturation
  • Response To Unfolded Protein
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 47 kDa heat shock protein| Anapl_15585| arsenic-transactivated protein 3| astp3| BERF-1| beta enolase repressor factor 1| CB1_000103015| CBP1| CBP2| cell proliferation-inducing gene 14 protein| collagen-binding protein| collagen binding protein 1| collagen binding protein 2| collagen-binding protein 2| colligin| colligin-1| colligin-2| EH28_06716| GP46| Gp50| GW7_02075| H920_14641| heat shock protein 47| Hsp47| J6| N325_08710| OI10| PAL_GLEAN10025514| PANDA_003323| PIG14| pprom| RA-A47| rheumatoid arthritis antigen A-47| rheumatoid arthritis-related antigen RA-A47| serine (or cysteine) peptidase inhibitor, clade H, member 1| serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1| serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)| serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2| serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2)| serine (or cysteine) proteinase inhibitor, clade H, member 1| serine protease inhibitor J6| serine proteinase inhibitor, clade H (heat shock protein 47), member 1| serpin H1| SERPINH2| serpin peptidase inhibitor, clade H (heat shock protein 47), mem| serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)| serpin peptidase inhibitor clade H member 1| serpin peptidase inhibitor, clade H , member 1| serpin peptidase inhibitor, clade H, member 1| TREES_T100008510| UY3_09367| Y1Q_003062| serpinh1

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