The Function of SEMA6D
Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.
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Protein names
Recommended name:
Semaphorin-6D- RS12900158 (SEMA6D) ??
- RS16958536 (SEMA6D) ??
- RS188133 (SEMA6D) ??
- RS1898111 (SEMA6D) ??
- RS8028579 (SEMA6D) ??
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Top Gene-Substance Interactions
Substances That Increase SEMA6D
| Substances | Interaction | Organism | Category |
Substances That Decrease SEMA6D
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Negative Regulation Of Axon Extension Involved In Axon Guidance
- Negative Regulation Of Smooth Muscle Cell Migration
- Neural Crest Cell Migration
- Positive Regulation Of Cell Migration
- Positive Regulation Of Smooth Muscle Cell Migration
- Semaphorin-Plexin Signaling Pathway
- Ventricular System Development