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  3. SEMA6D

SEMA6D (Semaphorin 6D)

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The Function of SEMA6D

Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.

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Protein names

Recommended name:

Semaphorin-6D

SEMA6D SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS12900158 (SEMA6D) ??
  2. RS16958536 (SEMA6D) ??
  3. RS188133 (SEMA6D) ??
  4. RS1898111 (SEMA6D) ??
  5. RS8028579 (SEMA6D) ??

Top Gene-Substance Interactions

Substances That Increase SEMA6D

Substances Interaction Organism Category

Substances That Decrease SEMA6D

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • CUTL1
  • Pax-6
  • Nkx3-1 v1
  • Nkx3-1
  • MIF-1

Gene Pathways:

  • Axon guidance

Molecular Function:

  • Chemorepellent Activity
  • Semaphorin Receptor Binding

Biological Processes:

  • Negative Regulation Of Axon Extension Involved In Axon Guidance
  • Negative Regulation Of Smooth Muscle Cell Migration
  • Neural Crest Cell Migration
  • Positive Regulation Of Cell Migration
  • Positive Regulation Of Smooth Muscle Cell Migration
  • Semaphorin-Plexin Signaling Pathway
  • Ventricular System Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Semaphorin-6A| semaphorin-6D| A306_09866| Anapl_06885| AS27_00102| AS28_07865| CB1_001602004| D330011G23| D623_10025755| H920_08830| I79_011934| M959_05305| MDA_GLEAN10007341| N300_13835| N301_09152| N302_16235| N303_08828| N307_09552| N308_02733| N310_12195| N311_05076| N312_03077| N320_06857| N322_04794| N325_04687| N326_06453| N327_03364| N329_07222| N330_05369| N331_04651| N336_08213| N341_01091| PAL_GLEAN10023507| sema domain, transmembrane domain , and cytoplasmic domain, 6D| sema domain, transmembrane domain (TM), and cytoplasmic domain| sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D| semaphorin-6C| semaphorin 6D4| TREES_T100018560| UY3_13711| Y1Q_024092| Y956_09808| Z169_06711| sema6d

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