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  3. RPH3AL

RPH3AL (Rabphilin 3A-like (without C2 domains))

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The Function of RPH3AL

Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.

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Protein names

Recommended name:

Rab effector Noc2

Alternative name(s):

No C2 domains protein
Rabphilin-3A-like protein

RPH3AL SNPs

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  1. RS7217319 (RPH3AL) ??

Top Gene-Substance Interactions

Substances That Increase RPH3AL

Substances Interaction Organism Category

Substances That Decrease RPH3AL

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • FOXO4
  • GATA-1
  • IRF-2
  • Nkx5-1
  • HSF2
  • GATA-2
  • GATA-3
  • FOXC1

Tissue specificity:

Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.

Molecular Function:

  • Calcium Ion Binding
  • Clathrin Binding
  • Cytoskeletal Protein Binding
  • Syntaxin Binding

Biological Processes:

  • Exocytosis
  • Glucose Homeostasis
  • Intracellular Protein Transport
  • Negative Regulation Of G-Protein Coupled Receptor Protein Signaling Pathway
  • Positive Regulation Of Protein Secretion
  • Regulation Of Exocytosis
  • Vesicle Fusion
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| rabphilin 3A-like protein| CB1_000765127| D623_10015737| H920_13036| MDA_GLEAN10016871| N311_03884| N312_02276| N320_06320| N321_08005| N324_04838| N325_03135| N326_04475| N327_04282| N328_05000| N329_12993| N331_03270| N334_08636| N335_12796| N336_06682| N339_05635| N340_00491| N341_12712| NOC2| no C2 domains protein| PANDA_006489| rab effector Noc2| rab effector Noc2-like protein| rabphilin-3A| rabphilin-3A-like protein| TREES_T100019008| UY3_05027| Y1Q_009838| rph3al

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