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  3. RHOC

RHOC (Ras homolog family member C)

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The Function of RHOC

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.

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Protein names

Recommended name:

Rho-related GTP-binding protein RhoC

Alternative name(s):

Rho cDNA clone 9
h9

RHOC SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS76570619 (RHOC) ??

Top Gene-Substance Interactions

Substances That Increase RHOC

Substances Interaction Organism Category

Substances That Decrease RHOC

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • ER-alpha
  • GR
  • GR-alpha
  • GR-beta
  • p53
  • AP-1
  • c-Jun
  • c-Fos

Gene Pathways:

  • Regulation of actin cytoskeleton
  • Signal Transduction
  • Wnt signaling pathway
  • Adherens junction
  • Tight junction
  • TGF-beta signaling pathway
  • Vascular smooth muscle contraction

Molecular Function:

  • Gtp Binding
  • Signal Transducer Activity

Biological Processes:

  • Apical Junction Assembly
  • Cytokinesis
  • Positive Regulation Of I-Kappab Kinase/Nf-Kappab Signaling
  • Positive Regulation Of Lipase Activity
  • Regulation Of Small Gtpase Mediated Signal Transduction
  • Skeletal Muscle Satellite Cell Migration
  • Small Gtpase Mediated Signal Transduction
  • Wound Healing, Spreading Of Cells
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| GTP-binding protein| H9| ras homolog gene family, member A| A306_10196| aplysia ras-related homolog 9 (RhoC)| ARH9| Arhc| AS27_01938| AS28_04387| CB1_000639023| CRHOC| D623_10030001| GTPase cRhoC| GW7_03049| M91_03148| M959_04061| MDA_GLEAN10024783| N300_10471| N301_00781| N303_04986| N305_03343| N307_00100| N309_01826| N310_05226| N320_04882| oncogene RHO H9| PAL_GLEAN10017408| protein phosphatase 1J| ras homolog 9 (RhoC)| ras homolog family member A| ras homolog gene family, member C| ras-like protein family member C| RAS-related homolog 9| RHOA| RhoA protein| rho cDNA clone 9| rhoC GTPase| RHOH9| rho-related GTP-binding protein RhoC| rho-related GTP-binding protein RhoC-like protein| SIG-61| silica-induced gene 61 protein| small GTP-binding protein RhoA| small GTP binding protein RhoC| TREES_T100005379| Y1Q_017910| Y956_09019| Z169_05349| rhoc

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