The Function of RHOC
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
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Protein names
Recommended name:
Rho-related GTP-binding protein RhoCAlternative name(s):
Rho cDNA clone 9h9
- RS76570619 (RHOC) ??
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Top Gene-Substance Interactions
Substances That Increase RHOC
| Substances | Interaction | Organism | Category |
Substances That Decrease RHOC
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Apical Junction Assembly
- Cytokinesis
- Positive Regulation Of I-Kappab Kinase/Nf-Kappab Signaling
- Positive Regulation Of Lipase Activity
- Regulation Of Small Gtpase Mediated Signal Transduction
- Skeletal Muscle Satellite Cell Migration
- Small Gtpase Mediated Signal Transduction
- Wound Healing, Spreading Of Cells