The Function of RGMB
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
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Protein names
Recommended name:
RGM domain family member BShort name:
DRAGONAlternative name(s):
DRG11-responsive axonal guidance and outgrowth of neuriteTop Gene-Substance Interactions
Substances That Increase RGMB
| Substances | Interaction | Organism | Category |
Substances That Decrease RGMB
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
Biological Processes:
- Cell Adhesion
- Signal Transduction
- Bmp Signaling Pathway
- Positive Regulation Of Transcription, Dna-Templated