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  3. RDH10

RDH10 (Retinol dehydrogenase 10)

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The Function of RDH10

Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.

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Protein names

Recommended name:

Retinol dehydrogenase 10

Alternative name(s):

Short chain dehydrogenase/reductase family 16C member 4

Top Gene-Substance Interactions

Substances That Increase RDH10

Substances Interaction Organism Category

Substances That Decrease RDH10

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Evi-1
  • PPAR-gamma1
  • HNF-1A
  • PPAR-gamma2
  • HNF-1
  • IRF-2
  • Pax-2
  • FOXC1

Tissue specificity:

Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle.

Gene Pathways:

  • Metabolic pathways
  • Disease
  • Signal Transduction
  • Retinol metabolism

Molecular Function:

  • Nadp-Retinol Dehydrogenase Activity
  • Retinol Dehydrogenase Activity

Biological Processes:

  • Bud Elongation Involved In Lung Branching
  • Ear Development
  • Embryonic Camera-Type Eye Development
  • Embryonic Forelimb Morphogenesis
  • Embryonic Viscerocranium Morphogenesis
  • Gonad Development
  • In Utero Embryonic Development
  • Metanephros Development
  • Neural Crest Cell Development
  • Nose Development
  • Primary Lung Bud Formation
  • Retinal Metabolic Process
  • Retinoic Acid Biosynthetic Process
  • Retinoid Metabolic Process
  • Retinol Metabolic Process
  • Visual Perception
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| null| A306_09945| CB1_000850019| D1Ertd762e| GW7_21394| H920_04566| I79_015551| m366Asp| M91_05814| MDA_GLEAN10021991| N303_14741| N309_03200| PAL_GLEAN10019347| PANDA_016329| rdh10-a| rdh10-b| Retinol dehydrogenase 10| SDR16C4| short chain dehydrogenase/reductase family 16C member 4| TREES_T100000030| UY3_10579| XRDH10| XRDH10a| XRDH10b| Y1Q_014394| rdh10

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