The Function of RDH10
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.
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Protein names
Recommended name:
Retinol dehydrogenase 10Alternative name(s):
Short chain dehydrogenase/reductase family 16C member 4Top Gene-Substance Interactions
Substances That Increase RDH10
| Substances | Interaction | Organism | Category |
Substances That Decrease RDH10
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle.
Gene Pathways:
Molecular Function:
Biological Processes:
- Retinoid Metabolic Process
- Metanephros Development
- In Utero Embryonic Development
- Retinoic Acid Biosynthetic Process
- Visual Perception
- Gonad Development
- Neural Crest Cell Development
- Embryonic Camera-Type Eye Development
- Embryonic Forelimb Morphogenesis
- Retinol Metabolic Process
- Retinal Metabolic Process
- Ear Development
- Nose Development
- Embryonic Viscerocranium Morphogenesis
- Primary Lung Bud Formation
- Bud Elongation Involved In Lung Branching