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  3. RBP4

RBP4 (Retinol binding protein 4)

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Summary of RBP4

A protein that binds to and delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

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Protein names

Recommended name:

Retinol-binding protein 4

Short name:

RBP

Alternative name(s):

Plasma retinol-binding protein
PRBP
1-182
1-181
1-179
1-176

Top Gene-Substance Interactions

RBP4 Interacts with These Diseases

Disease Score

Substances That Increase RBP4

Substances Interaction Organism Category

Substances That Decrease RBP4

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • AP-2gamma

Gene Pathways:

  • Disease
  • Signal Transduction

Molecular Function:

  • Retinal Binding
  • Retinol Binding
  • Retinol Transporter Activity

Biological Processes:

  • Cardiac Muscle Tissue Development
  • Embryonic Organ Morphogenesis
  • Embryonic Retina Morphogenesis In Camera-Type Eye
  • Embryonic Skeletal System Development
  • Eye Development
  • Female Genitalia Morphogenesis
  • Gluconeogenesis
  • Glucose Homeostasis
  • Heart Development
  • Heart Trabecula Formation
  • Lung Development
  • Maintenance Of Gastrointestinal Epithelium
  • Negative Regulation Of Cardiac Muscle Cell Proliferation
  • Positive Regulation Of Immunoglobulin Secretion
  • Positive Regulation Of Insulin Secretion
  • Response To Ethanol
  • Response To Retinoic Acid
  • Retinoid Metabolic Process
  • Retinol Metabolic Process
  • Retinol Transport
  • Urinary Bladder Development
  • Uterus Development
  • Vagina Development
  • Visual Perception

Drug Bank:

  • Vitamin A
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| RNA-binding protein 4| A306_06100| Anapl_03553| AS27_02625| AS28_12947| CB1_000689006| CG9654 gene product from transcript CG9654-RA| CG9654-PA| Dmel_CG9654| fb23c12| H920_08661| I79_006982| M91_12383| M959_09903| MCOPCB10| MDA_GLEAN10014836| N300_07483| N301_10625| N302_13508| N303_09169| N305_11478| N306_13889| N307_06161| N309_12994| N310_05201| N311_05127| N312_07521| N320_02923| N321_12436| N322_07449| N324_11934| N326_12484| N327_09365| N329_05073| N330_09741| N331_08958| N332_01296| N333_04059| N334_12574| N335_12260| N336_08798| N340_03028| PAL_GLEAN10018351| PANDA_004191| Plasma retinol-binding protein| Plasma retinol-binding protein 1| PRBP| RBP| Rbp-4| rbp4a| Rbp4-PA| RBPA| RDCCAS| retb1| retinol-binding protein 4| Retinol-binding protein 4-A| retinol binding protein 4, cellular| retinol-binding protein 4, interstitial| retinol binding protein 4, plasma| rrm4| serum retinol binding protein| srbp| testis specific RRM protein| TREES_T100006457| TSR| UY3_00520| Y1Q_000078| Y956_01498| rbp4

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