The Function of RASGEF1B
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
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Protein names
Recommended name:
Ras-GEF domain-containing family member 1BAlternative name(s):
GPI gamma-4- RS1662853 (RASGEF1B) ??
- RS17556750 (RASGEF1B) ??
- RS1878528 (RASGEF1B) ??
- RS2011962 (RASGEF1B) ??
- RS710841 (RASGEF1B) ??
- RS788867 (RASGEF1B) ??
- RS994014 (RASGEF1B) ??
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Top Gene-Substance Interactions
Substances That Increase RASGEF1B
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Substances That Decrease RASGEF1B
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Induction:
Up-regulated in macrophages stimulated with IFNG, GPI-mucins or bacterial lipopolysaccharides (LPS).