The Function of RASGEF1A
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.
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- RS28461806 (RASGEF1A) ??
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Top Gene-Substance Interactions
Substances That Increase RASGEF1A
| Substances | Interaction | Organism | Category |
Substances That Decrease RASGEF1A
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Detected in brain and spinal cord. Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies.
Molecular Function:
Biological Processes:
- Mapk Cascade
- Positive Regulation Of Ras Protein Signal Transduction
- Small Gtpase Mediated Signal Transduction