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  3. RAN

RAN (RAN, member RAS oncogene family)

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The Function of RAN

Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.

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Protein names

Recommended name:

GTP-binding nuclear protein Ran

Alternative name(s):

Androgen receptor-associated protein 24
GTPase Ran
Ras-like protein TC4
Ras-related nuclear protein

RAN SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS14035 (RAN) ??
  2. RS7299940 (RAN) ??
  3. RS7304057 (RAN) ??

Top Gene-Substance Interactions

RAN Interacts with These Diseases

Disease Score

Substances That Increase RAN

Substances Interaction Organism Category

Substances That Decrease RAN

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • GR
  • GR-alpha
  • GR-beta
  • p53
  • Max
  • NF-kappaB1
  • C/EBPalpha
  • c-Rel

Tissue specificity:

Expressed in a variety of tissues.

Gene Pathways:

  • Metabolism
  • Disease
  • Gene Expression
  • RNA transport
  • Ribosome biogenesis in eukaryotes

Molecular Function:

  • Androgen Receptor Binding
  • Cadherin Binding Involved In Cell-Cell Adhesion
  • Chromatin Binding
  • Gdp Binding
  • Gtpase Activity
  • Gtp Binding
  • Poly(A) Rna Binding
  • Transcription Coactivator Activity

Biological Processes:

  • Actin Cytoskeleton Organization
  • Androgen Receptor Signaling Pathway
  • Cell Division
  • Cellular Protein Complex Localization
  • Dna Metabolic Process
  • Gene Silencing By Rna
  • Intracellular Transport Of Virus
  • Mitotic Nuclear Division
  • Mitotic Spindle Organization
  • Positive Regulation Of Transcription, Dna-Templated
  • Pre-Mirna Export From Nucleus
  • Protein Export From Nucleus
  • Protein Import Into Nucleus
  • Protein Import Into Nucleus, Translocation
  • Protein Localization To Nucleolus
  • Protein Transmembrane Transport
  • Ribosomal Large Subunit Export From Nucleus
  • Ribosomal Small Subunit Export From Nucleus
  • Signal Transduction
  • Small Gtpase Mediated Signal Transduction
  • Trna Export From Nucleus
  • Viral Process
  • Cellular Response To Mineralocorticoid Stimulus
  • Hippocampus Development
  • Spermatid Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| GTP-binding protein| AAF30287| androgen receptor-associated protein 24| ara24| AS27_14394| AS28_08418| CG1404 gene product from transcript CG1404-RC| CG1404-PA| CG1404-PB| CG1404-PC| CG1404-PD| D623_10005195| Dmel_CG1404| dran| fc16b04| GekBS156P| gsp1| GTPase Ran| GTP-binding nuclear protein Ran| GTP-binding nuclear protein Ran-B-2| GTP-binding nuclear protein Ran-like protein| guanosine triphosphatase Ran| H920_15045| I79_024397| M91_09492| M959_10174| member RAS oncogene family| N300_08214| N301_08263| N302_01278| N303_02170| N305_06832| N306_06504| N307_14145| N308_04219| N309_06761| N310_00409| N311_08008| N312_10575| N320_10760| N321_14006| N322_11448| N324_04997| N325_05047| N326_09436| N327_06559| N328_10561| N329_03856| N330_04794| N331_00407| N332_03185| N333_10073| N334_12288| N335_12130| N336_10162| N339_08192| N340_09371| N341_08628| OK/SW-cl.81| PANDA_019898| putative RAN member RAS oncogene family variant 1| Q9VZ23| ran-1| ran10A| RanGTP| RanGTPase| Ran GTPase| RAN member RAS oncogene family-like| RAN, member RAS oncogene family pseudogene 1| RANP1| Ran-PA| Ran-PB| Ran-PC| Ran-PD| RanTC4| ras-like protein TC4| RAS oncogene family protein RAN| ras-related nuclear protein| tc4| TREES_T100020470| Y1Q_017921| Y956_05955| Z169_05455| ran

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