The Function of RAN
Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
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Protein names
Recommended name:
GTP-binding nuclear protein RanAlternative name(s):
Androgen receptor-associated protein 24GTPase Ran
Ras-like protein TC4
Ras-related nuclear protein
- RS14035 (RAN) ??
- RS7299940 (RAN) ??
- RS7304057 (RAN) ??
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Top Gene-Substance Interactions
RAN Interacts with These Diseases
Disease | Score |
Substances That Increase RAN
Substances | Interaction | Organism | Category |
Substances That Decrease RAN
Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in a variety of tissues.
Molecular Function:
- Androgen Receptor Binding
- Cadherin Binding Involved In Cell-Cell Adhesion
- Chromatin Binding
- Gdp Binding
- Gtpase Activity
- Gtp Binding
- Poly(A) Rna Binding
- Transcription Coactivator Activity
Biological Processes:
- Actin Cytoskeleton Organization
- Androgen Receptor Signaling Pathway
- Cell Division
- Cellular Protein Complex Localization
- Dna Metabolic Process
- Gene Silencing By Rna
- Intracellular Transport Of Virus
- Mitotic Nuclear Division
- Mitotic Spindle Organization
- Positive Regulation Of Transcription, Dna-Templated
- Pre-Mirna Export From Nucleus
- Protein Export From Nucleus
- Protein Import Into Nucleus
- Protein Import Into Nucleus, Translocation
- Protein Localization To Nucleolus
- Protein Transmembrane Transport
- Ribosomal Large Subunit Export From Nucleus
- Ribosomal Small Subunit Export From Nucleus
- Signal Transduction
- Small Gtpase Mediated Signal Transduction
- Trna Export From Nucleus
- Viral Process
- Cellular Response To Mineralocorticoid Stimulus
- Hippocampus Development
- Spermatid Development