The Function of RAB8B
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Ras-related protein Rab-8B- RS1986112 (RAB8B) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
Substances That Increase RAB8B
| Substances | Interaction | Organism | Category |
Substances That Decrease RAB8B
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Molecular Function:
Biological Processes:
- Adherens Junction Organization
- Antigen Processing And Presentation
- Positive Regulation Of Cell Projection Organization
- Positive Regulation Of Corticotropin Secretion
- Protein Import Into Peroxisome Membrane
- Protein Secretion
- Small Gtpase Mediated Signal Transduction
- Vesicle Docking Involved In Exocytosis