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  3. RAB8B

RAB8B (RAB8B, member RAS oncogene family)

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The Function of RAB8B

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells.

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Protein names

Recommended name:

Ras-related protein Rab-8B

RAB8B SNPs

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  1. RS1986112 (RAB8B) ??

Top Gene-Substance Interactions

Substances That Increase RAB8B

Substances Interaction Organism Category

Substances That Decrease RAB8B

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • FOXO4
  • GATA-1
  • NF-E2
  • NF-E2 p45
  • Bach2
  • GATA-2
  • GATA-3
  • FOXC1
  • LCR-F1

Molecular Function:

  • Gdp Binding
  • Gtpase Activity
  • Gtp Binding
  • Receptor Binding

Biological Processes:

  • Adherens Junction Organization
  • Antigen Processing And Presentation
  • Positive Regulation Of Cell Projection Organization
  • Positive Regulation Of Corticotropin Secretion
  • Protein Import Into Peroxisome Membrane
  • Protein Secretion
  • Small Gtpase Mediated Signal Transduction
  • Vesicle Docking Involved In Exocytosis
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 5930437D16| A306_15256| AS28_07299| EGK_17569| GTPase Rab8b| GW7_00144| H920_12579| M959_05226| MDA_GLEAN10015336| N300_15024| N301_08924| N302_04868| N303_01380| N305_07849| N306_15247| N307_11139| N308_02817| N309_05812| N311_02931| N312_05200| N321_09973| N322_09150| N324_06081| N325_02395| N326_10602| N327_10974| N328_04316| N329_01412| N330_09044| N331_11124| N332_02768| N334_11800| N335_12080| N336_04981| N339_03725| N340_11836| PAL_GLEAN10023405| PANDA_002150| RAB44, member RAS oncogene family| RAB-8b protein| Ras-related protein Rab-8| ras-related protein Rab-8B| Ras-related protein Rab-8B-like protein| UY3_15663| XELAEV_18020805mg| Y1Q_029064| Y956_05521| Z169_06593| rab8b

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