• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. RAB31

RAB31 (RAB31, member RAS oncogene family)

Loading...

The Function of RAB31

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Ras-related protein Rab-31

Alternative name(s):

Ras-related protein Rab-22B

RAB31 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS7233332 (RAB31) ??

Top Gene-Substance Interactions

Substances That Increase RAB31

Substances Interaction Organism Category

Substances That Decrease RAB31

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GATA-1
  • Lmo2
  • E4BP4
  • USF1
  • USF-1

Tissue specificity:

Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.

Molecular Function:

  • Gdp Binding
  • Gtpase Activity
  • Gtp Binding

Biological Processes:

  • Cellular Response To Insulin Stimulus
  • Golgi To Plasma Membrane Protein Transport
  • Phagosome Maturation
  • Receptor Internalization
  • Regulated Exocytosis
  • Small Gtpase Mediated Signal Transduction
  • Golgi Vesicle Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_07286| Anapl_06607| AS27_05797| CB1_000932041| D623_10029827| GTP-binding protein Rab0| I79_016329| M91_17972| monomeric GTP-binding protein| N300_05308| N301_14012| N302_08980| N303_01602| N305_03498| N306_08993| N308_00775| N310_13580| N320_00341| N321_14002| N322_02885| N324_10918| N325_06497| N329_07056| N330_01912| N331_10596| N333_12310| N334_06308| N336_08484| N339_11326| N340_13446| N341_01151| PAL_GLEAN10023229| PANDA_010679| Rab0| Rab22B| ras-related protein Rab-22B| Ras-related protein Rab-31| UY3_09409| Y1Q_002394| Y956_15419| Z169_05782| rab31

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved