The Function of PYGB
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
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Protein names
Recommended name:
Glycogen phosphorylase, brain form- RS139672965 (PYGB) ??
- RS2281558 (PYGB) ??
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Top Gene-Substance Interactions
Substances That Increase PYGB
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Substances That Decrease PYGB
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Enzyme Regulation:
Activity of phosphorylase is controlled both by allosteric means (through the non-covalent binding of metabolites) and by covalent modification. Thus AMP allosterically activates, whereas ATP, ADP, and glucose-6-phosphate allosterically inhibit, phosphorylase B.