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  3. PROS1

PROS1 (Protein S (alpha))

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The Function of PROS1

Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.

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Protein names

Recommended name:

Vitamin K-dependent protein S

PROS1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS60136336 (PROS1) ??

Top Gene-Substance Interactions

PROS1 Interacts with These Diseases

Disease Score

Substances That Increase PROS1

Substances Interaction Organism Category

Substances That Decrease PROS1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • STAT3
  • C/EBPbeta
  • HNF-4alpha1
  • HNF-4alpha2
  • Sp1
  • SREBP-1a
  • SREBP-1b

Tissue specificity:

Plasma.

Gene Pathways:

  • Immune System
  • Metabolism of proteins
  • Hemostasis
  • Complement and coagulation cascades

Molecular Function:

  • Calcium Ion Binding
  • Endopeptidase Inhibitor Activity

Biological Processes:

  • Blood Coagulation
  • Er To Golgi Vesicle-Mediated Transport
  • Fibrinolysis
  • Leukocyte Migration
  • Peptidyl-Glutamic Acid Carboxylation
  • Platelet Degranulation
  • Regulation Of Complement Activation
  • Signal Peptide Processing
  • Positive Regulation Of Phagocytosis
  • Response To Lipopolysaccharide

Drug Bank:

  • Drotrecogin Alfa
  • Menadione
  • Sodium Tetradecyl Sulfate
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| PSA| A306_07202| AS28_01792| D623_10012248| GW7_07640| H920_14459| I79_002836| M959_00303| MDA_GLEAN10010287| N300_10717| N301_11594| N302_12891| N303_03273| N305_10303| N306_13189| N307_14345| N308_09667| N309_04731| N310_03307| N311_05271| N320_11435| N321_01539| N322_10103| N324_05956| N328_06200| N329_11055| N330_04680| N331_04157| N332_03602| N334_04273| N335_04266| N336_12833| N339_10028| N340_12971| N341_09743| PAL_GLEAN10016398| PANDA_019515| Pros| protein Sa| PS21| PS22| PS23| PS24| PS25| THPH5| THPH6| TREES_T100012775| UY3_04932| vitamin K-dependent plasma protein S| Vitamin K-dependent protein S| vitamin K-dependent protein S-like protein| vitamin K-dependent protein S preproprotein| Y1Q_030339| Y956_09497| Z169_06376| pros1

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