The Function of PROS1
Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
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Protein names
Recommended name:
Vitamin K-dependent protein S- RS60136336 (PROS1) ??
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Top Gene-Substance Interactions
PROS1 Interacts with These Diseases
| Disease | Score |
Substances That Increase PROS1
| Substances | Interaction | Organism | Category |
Substances That Decrease PROS1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Plasma.
Molecular Function:
Biological Processes:
- Blood Coagulation
- Er To Golgi Vesicle-Mediated Transport
- Fibrinolysis
- Leukocyte Migration
- Peptidyl-Glutamic Acid Carboxylation
- Platelet Degranulation
- Regulation Of Complement Activation
- Signal Peptide Processing
- Positive Regulation Of Phagocytosis
- Response To Lipopolysaccharide
Drug Bank:
- Drotrecogin Alfa
- Menadione
- Sodium Tetradecyl Sulfate