The Function of PRKAR2B
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
cAMP-dependent protein kinase type II-beta regulatory subunit- RS13224682 (PRKAR2B) ??
- RS3752645 (PRKAR2B) ??
- RS7779057 (PRKAR2B) ??
- RS7798500 (PRKAR2B) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
PRKAR2B Interacts with These Diseases
Disease | Score |
Substances That Increase PRKAR2B
Substances | Interaction | Organism | Category |
Substances That Decrease PRKAR2B
Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|
Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Gene Pathways:
Molecular Function:
- Camp Binding
- Camp-Dependent Protein Kinase Inhibitor Activity
- Camp-Dependent Protein Kinase Regulator Activity
- Protein Kinase A Catalytic Subunit Binding
- Ubiquitin Protein Ligase Binding
Biological Processes:
- Activation Of Protein Kinase A Activity
- Blood Coagulation
- Cellular Response To Glucagon Stimulus
- Fatty Acid Metabolic Process
- G2/M Transition Of Mitotic Cell Cycle
- Intracellular Signal Transduction
- Learning
- Negative Regulation Of Camp-Dependent Protein Kinase Activity
- Renal Water Homeostasis
- Response To Antipsychotic Drug
- Response To Clozapine