• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. PRCP

PRCP (Prolylcarboxypeptidase)

Loading...

The Function of PRCP

Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Lysosomal Pro-X carboxypeptidase

Short name:

PRCP

Alternative name(s):

Angiotensinase C
Lysosomal carboxypeptidase C
Proline carboxypeptidase
Prolylcarboxypeptidase

PRCP SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2298668 (PRCP) ??

Top Gene-Substance Interactions

Substances That Increase PRCP

Substances Interaction Organism Category

Substances That Decrease PRCP

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-YB
  • NF-YC

Tissue specificity:

Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.

Molecular Function:

  • Dipeptidyl-Peptidase Activity
  • Serine-Type Carboxypeptidase Activity

Biological Processes:

  • Angiogenesis Involved In Wound Healing
  • Blood Coagulation, Intrinsic Pathway
  • Energy Homeostasis
  • Glucose Homeostasis
  • Negative Regulation Of Systemic Arterial Blood Pressure
  • Plasma Kallikrein-Kinin Cascade
  • Regulation Of Blood Vessel Endothelial Cell Migration
  • Regulation Of Reactive Oxygen Species Metabolic Process
  • Regulation Of Thyroid Hormone Mediated Signaling Pathway
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| PCP| A306_10291| angiotensinase C| AS27_03948| AS28_14388| CB1_000916021| D623_10012566| H920_08116| humpcp| lysosomal carboxypeptidase C| lysosomal Pro-X carboxypeptidase| lysosomal Pro-X carboxypeptidase isoform 1 preproprotein| M959_12022| MDA_GLEAN10011382| N300_01737| N301_00148| N302_10813| N303_02392| N305_13130| N306_00082| N308_00683| N309_13811| N310_12415| N311_09956| N312_11438| N320_06688| N321_10989| N325_12104| N326_06081| N329_11722| N330_14011| N331_04874| N332_00896| N333_12015| N334_05512| N335_13114| N336_02340| N339_00711| N340_14647| N341_07179| PAL_GLEAN10025550| PANDA_014943| proline carboxypeptidase| prolylcarboxypeptidase (angiotensinase C)| UY3_07818| Y1Q_017406| Y956_13419| Z169_04000| prcp

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved