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  3. PPP3CA

PPP3CA (Protein phosphatase 3 catalytic subunit alpha)

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The Function of PPP3CA

Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.

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Protein names

Recommended name:

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

Alternative name(s):

CAM-PRP catalytic subunit
Calmodulin-dependent calcineurin A subunit alpha isoform

PPP3CA SNPs

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  1. RS13107740 (PPP3CA) ??
  2. RS1405687 (PPP3CA) ??
  3. RS17030795 (PPP3CA) ??
  4. RS2659546 (PPP3CA) ??
  5. RS72927357 (PPP3CA) ??

Top Gene-Substance Interactions

PPP3CA Interacts with These Diseases

Disease Score

Substances That Increase PPP3CA

Substances Interaction Organism Category

Substances That Decrease PPP3CA

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

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