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  3. PPIL1

PPIL1 (Peptidylprolyl isomerase like 1)

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The Function of PPIL1

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.

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Protein names

Recommended name:

Peptidyl-prolyl cis-trans isomerase-like 1

Alternative name(s):

PPIase
Rotamase PPIL1

Top Gene-Substance Interactions

Substances That Increase PPIL1

Substances Interaction Organism Category

Substances That Decrease PPIL1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Lmo2
  • E47

Tissue specificity:

Ubiquitous, with the most abundant expression in heart and skeletal muscle.

Enzyme Regulation:

Inhibited by Cyclosporin A.

Molecular Function:

  • Peptidyl-Prolyl Cis-Trans Isomerase Activity

Biological Processes:

  • Mrna Splicing, Via Spliceosome
  • Protein Folding
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CYPL1| PPIase| peptidyl-prolyl cis-trans isomerase| CB1_069740006| CGI-124| cyclophilin like 1| cyclophilin-related gene 1| D623_10002166| EGK_14845| EH28_14211| GW7_15685| H920_11601| hCyPX| MDA_GLEAN10010710| N301_11103| N302_12584| N303_12939| N305_03379| N310_11830| N333_03588| PAL_GLEAN10007034| PANDA_002207| Peptidyl-prolyl cis-trans isomerase-like 1| peptidyl-prolyl cis-trans isomerase-like 1-like| peptidyl-prolyl cis-trans isomerase-like 1-like protein| peptidyl-prolyl cis-trans isomerase-like-like protein| peptidylprolyl isomerase (cyclophilin)-like 1| rotamase PPIL1| TREES_T100014925| UY3_17057| Y1Q_003793| ppil1

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