The Function of PPIL1
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.
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Protein names
Recommended name:
Peptidyl-prolyl cis-trans isomerase-like 1Alternative name(s):
PPIaseRotamase PPIL1
Top Gene-Substance Interactions
Substances That Increase PPIL1
| Substances | Interaction | Organism | Category |
Substances That Decrease PPIL1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Ubiquitous, with the most abundant expression in heart and skeletal muscle.
Enzyme Regulation:
Inhibited by Cyclosporin A.