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  3. PLA2G4F

PLA2G4F (Phospholipase A2 group IVF)

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The Function of PLA2G4F

Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine.

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Protein names

Recommended name:

Cytosolic phospholipase A2 zeta

Alternative name(s):

cPLA2-zeta
Phospholipase A2 group IVF

PLA2G4F SNPs

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  1. RS1356410 (PLA2G4F) ??

Top Gene-Substance Interactions

Substances That Increase PLA2G4F

Substances Interaction Organism Category

Substances That Decrease PLA2G4F

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • ER-alpha
  • Evi-1
  • CUTL1
  • NF-kappaB1

Enzyme Regulation:

Stimulated by cytosolic Ca(2+).

Molecular Function:

  • Calcium-Dependent Phospholipase A2 Activity
  • Lysophospholipase Activity
  • Metal Ion Binding
  • Phosphatidylcholine 1-Acylhydrolase Activity
  • Phospholipase A2 Activity

Biological Processes:

  • Arachidonic Acid Secretion
  • Cellular Response To Antibiotic
  • Cellular Response To Organic Cyclic Compound
  • Phosphatidylcholine Acyl-Chain Remodeling
  • Phosphatidylethanolamine Acyl-Chain Remodeling
  • Phosphatidylglycerol Acyl-Chain Remodeling
  • Phosphatidylinositol Acyl-Chain Remodeling
  • Phosphatidylserine Acyl-Chain Remodeling
  • Phospholipid Catabolic Process
  • Phospholipid Metabolic Process
  • Prostaglandin Biosynthetic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| null| A306_07960| AS27_02335| cPLA2-zeta| Cytosolic phospholipase A2 zeta| H920_05585| I79_003806| M91_00952| M959_11727| N300_13256| N301_08558| N302_01622| N303_08203| N305_09523| N306_08093| N307_11658| N310_13003| N311_12480| N312_12250| N320_06949| N321_14222| N324_10429| N325_05954| N326_09306| N327_12992| N328_01991| N329_09863| N330_07419| N332_13333| N333_10168| N334_01302| N335_02199| N336_08313| N339_12780| N340_13145| PAL_GLEAN10023577| PANDA_001040| phospholipase A2, group IVF| PLA2G4FZ| Pla2zeta| UY3_03187| Y956_16610| Z169_12284| pla2g4f

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