The Function of PGD
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
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Protein names
Recommended name:
6-phosphogluconate dehydrogenase, decarboxylatingTop Gene-Substance Interactions
Substances That Increase PGD
| Substances | Interaction | Organism | Category |
Substances That Decrease PGD
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Pentose-Phosphate Shunt
- Pentose-Phosphate Shunt, Oxidative Branch
- Pentose Biosynthetic Process
- D-Gluconate Metabolic Process
- Oxidation-Reduction Process
Drug Bank:
- Gadopentetate Dimeglumine
- Furosemide
- Meloxicam
- Methotrexate
- Ritodrine
- Dacarbazine
- Ketotifen