• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. PFKP

PFKP (Phosphofructokinase, platelet)

Loading...

Summary of PFKP

PFKP (phosphofructokinase, platelet) encodes a protein that is a key regulatory enzyme in glycolysis (R). 

0 users want this gene increased, 0 users want it decreased

The Function of PFKP

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.

Protein names

Recommended name:

ATP-dependent 6-phosphofructokinase, platelet type

Short name:

PFK-P

Alternative name(s):

ATP-PFK
6-phosphofructokinase type C
Phosphofructo-1-kinase isozyme C
PFK-C
Phosphohexokinase

PFKP SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS6602024 (PFKP) ??
  2. RS7896691 (PFKP) ??

Top Gene-Substance Interactions

Substances That Increase PFKP

Substances Interaction Organism Category

Substances That Decrease PFKP

Substances Interaction Organism Category

Advanced Summary

PFKP (phosphofructokinase, platelet) encodes a protein that is a key regulatory enzyme in glycolysis (R). 

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Arnt
  • STAT3
  • MEF-2A
  • STAT5A
  • STAT5B
  • IRF-1
  • STAT2
  • STAT4

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Disease
  • Fructose and mannose metabolism
  • Glycolysis / Gluconeogenesis
  • Pentose phosphate pathway
  • Galactose metabolism

Enzyme Regulation:

Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.

Molecular Function:

  • 6-Phosphofructokinase Activity
  • Atp Binding
  • Cadherin Binding Involved In Cell-Cell Adhesion
  • Metal Ion Binding
  • Protein Complex Binding

Biological Processes:

  • Canonical Glycolysis
  • Fructose 6-Phosphate Metabolic Process
  • Mitophagy In Response To Mitochondrial Depolarization
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| ATP-PFK| PFK| phosphofructokinase 1| phosphohexokinase| phosphofructokinase| 6-phosphofructo-1-kinase, C-type| 6-phosphofructokinase, platelet type| 6-phosphofructokinase type C| 6-phosphofructokinase type C-like| AS28_03980| ATP-dependent 6-phosphofructokinase, platelet type| ATP:D-fructose 6-phosphate 1-phosphotransferase| CB1_000294032| H920_13613| M91_01955| M959_03697| MDA_GLEAN10016424| N300_13614| N301_13481| N302_03997| N303_03822| N305_14495| N306_00712| N307_00584| N308_06792| N309_07356| N310_12995| N311_08732| N312_11413| N320_02437| N321_07943| N322_12657| N324_00394| N325_07653| N329_10275| N331_02634| N332_09664| N333_12362| N334_12807| N341_01900| PAL_GLEAN10001861| PANDA_010135| pfk1| pfkc| PFK-C| pfkf| PFKM| PFK-P| PFKP_tv1| phosphofructo-1-kinase isozyme C| phosphofructokinase C isozyme| phosphofructokinase C-type subunit| phosphofructokinase, muscle| TREES_T100002455| UY3_01641| Y1Q_008867| Y956_00138| Z169_13526| pfkp

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved