The Function of PFKFB3
Synthesis and degradation of fructose 2,6-bisphosphate.
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Protein names
Recommended name:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3Alternative name(s):
6PF-2-K/Fru-2,6-P2ase 3PFK/FBPase 3
6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme
Renal carcinoma antigen NY-REN-56
iPFK-2
- RS11257188 (PFKFB3) ??
- RS7077335 (PFKFB3) ??
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Top Gene-Substance Interactions
PFKFB3 Interacts with These Diseases
| Disease | Score |
Substances That Increase PFKFB3
| Substances | Interaction | Organism | Category |
Substances That Decrease PFKFB3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Ubiquitous.
Gene Pathways:
Molecular Function:
Biological Processes:
- Fructose Metabolic Process
- Fructose 2,6-Bisphosphate Metabolic Process
- Brain Development
- Canonical Glycolysis