The Function of PEX5
Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
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Protein names
Recommended name:
Peroxisomal targeting signal 1 receptorShort name:
PTS1RAlternative name(s):
PTS1 receptorPTS1-BP
Peroxin-5
Peroxisomal C-terminal targeting signal import receptor
Peroxisome receptor 1
Top Gene-Substance Interactions
Substances That Increase PEX5
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Substances That Decrease PEX5
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Gene Pathways:
Molecular Function:
- Enzyme Binding
- Peroxisome Matrix Targeting Signal-1 Binding
- Peroxisome Targeting Sequence Binding
- Protein C-Terminus Binding
- Protein N-Terminus Binding
- Small Gtpase Binding
Biological Processes:
- Negative Regulation Of Protein Homotetramerization
- Protein Import Into Peroxisome Matrix
- Protein Import Into Peroxisome Matrix, Docking
- Protein Import Into Peroxisome Matrix, Translocation
- Protein Import Into Peroxisome Membrane
- Protein Targeting To Peroxisome
- Protein Tetramerization