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  3. PCBD2

PCBD2 (Pterin-4 alpha-carbinolamine dehydratase 2)

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The Function of PCBD2

Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.

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Protein names

Recommended name:

Pterin-4-alpha-carbinolamine dehydratase 2

Short name:

PHS 2

Alternative name(s):

4-alpha-hydroxy-tetrahydropterin dehydratase 2
DcoH-like protein DCoHm
Dimerization cofactor of hepatocyte nuclear factor 1 from muscle
HNF-1-alpha dimerization cofactor

PCBD2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS319598 (PCBD2) ??

Top Gene-Substance Interactions

Substances That Increase PCBD2

Substances Interaction Organism Category

Substances That Decrease PCBD2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • Pax-3
  • HNF-4alpha1
  • HNF-4alpha2

Molecular Function:

  • 4-Alpha-Hydroxytetrahydrobiopterin Dehydratase Activity
  • Phenylalanine 4-Monooxygenase Activity

Biological Processes:

  • Positive Regulation Of Transcription, Dna-Templated
  • Protein Heterooligomerization
  • Protein Homotetramerization
  • Tetrahydrobiopterin Biosynthetic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| PHS2| 4-alpha-hydroxy-tetrahydropterin dehydratase 2| 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2| A306_14587| Anapl_09835| AS27_12068| AS28_08190| D623_10032610| Dcoh2| DCoH-alpha| dcoH-like protein DCoHm| Dcohm| dimerization cofactor of hepatocyte nuclear factor 1 alpha 2| dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)| dimerization cofactor of hepatocyte nuclear factor 1 from muscle| dimerization cofactor of hepatocyte nuclear factor 1 (HNF1) from muscle| hepatocyte nuclear factor 1a dimerization cofactor isoform| HNF-1-alpha dimerization cofactor| M91_21042| M959_09655| MDA_GLEAN10012367| N300_11041| N301_09272| N302_12390| N303_10936| N305_11406| N306_10427| N307_10078| N308_10617| N309_09149| N312_01490| N320_06143| N322_04469| N324_01215| N325_12316| N327_12166| N328_04430| N330_02992| N331_00874| N332_11619| N336_11901| N339_02615| N340_03905| N341_09740| PAL_GLEAN10016855| PANDA_000761| PHS 2| Pterin-4-alpha-carbinolamine dehydratase 2| pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2| pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2| pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 pseudogene| UY3_01134| Y1Q_020377| Y956_06228| Z169_10554| pcbd2

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