The Function of OLFM1
Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
NoelinAlternative name(s):
Neuronal olfactomedin-related ER localized proteinOlfactomedin-1
- RS10776934 (OLFM1) ??
- RS3849221 (OLFM1) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
OLFM1 Interacts with These Diseases
| Disease | Score |
Substances That Increase OLFM1
| Substances | Interaction | Organism | Category |
Substances That Decrease OLFM1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Biological Processes:
- Atrioventricular Valve Formation
- Cardiac Epithelial To Mesenchymal Transition
- Negative Regulation Of Gene Expression
- Nervous System Development
- Neuronal Signal Transduction
- Positive Regulation Of Epithelial To Mesenchymal Transition
- Positive Regulation Of Gene Expression
- Regulation Of Axon Extension