The Function of OLFM1
Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli.
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Protein names
Recommended name:
NoelinAlternative name(s):
Neuronal olfactomedin-related ER localized proteinOlfactomedin-1
- RS10776934 (OLFM1) ??
- RS3849221 (OLFM1) ??
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Top Gene-Substance Interactions
OLFM1 Interacts with These Diseases
| Disease | Score |
Substances That Increase OLFM1
| Substances | Interaction | Organism | Category |
Substances That Decrease OLFM1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Biological Processes:
- Atrioventricular Valve Formation
- Nervous System Development
- Positive Regulation Of Gene Expression
- Negative Regulation Of Gene Expression
- Positive Regulation Of Epithelial To Mesenchymal Transition
- Neuronal Signal Transduction
- Regulation Of Axon Extension
- Cardiac Epithelial To Mesenchymal Transition