Summary of NUTF2
The gene codes for a protein, nuclear transport factor 2. It aids protein transport into the nucleus [R].
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The Function of NUTF2
Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.
Protein names
Recommended name:
Nuclear transport factor 2Short name:
PP15Alternative name(s):
NTF-2Placental protein 15
- RS2271293 (NUTF2) ??
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Top Gene-Substance Interactions
Substances That Increase NUTF2
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Substances That Decrease NUTF2
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Molecular Function:
Biological Processes:
- Protein Import Into Nucleus, Translocation
- Protein Import Into Nucleus
- Protein Export From Nucleus
- Positive Regulation Of Protein Import Into Nucleus
- Mrna Transport
- Protein Localization To Nuclear Pore
- Negative Regulation Of Vascular Endothelial Growth Factor Production