Summary of NUCB2
The gene codes for a protein, nucleobindin 2. It plays a role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells [R].
0 users want this gene increased,
0 users want it decreased
The Function of NUCB2
Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Protein names
Recommended name:
Nucleobindin-2Alternative name(s):
DNA-binding protein NEFAGastric cancer antigen Zg4
Prepronesfatin
- RS1330 (NUCB2) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
NUCB2 Interacts with These Diseases
| Disease | Score |
Substances That Increase NUCB2
| Substances | Interaction | Organism | Category |
Substances That Decrease NUCB2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Predominantly expressed in spleen, testis and normal stomach.