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  3. NT5C1B

NT5C1B (5'-nucleotidase, cytosolic IB)

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The Function of NT5C1B

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.

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Protein names

Recommended name:

Cytosolic 5'-nucleotidase 1B

Alternative name(s):

cN1B
Autoimmune infertility-related protein
Cytosolic 5'-nucleotidase IB
cN-IB

Top Gene-Substance Interactions

Substances That Increase NT5C1B

Substances Interaction Organism Category

Substances That Decrease NT5C1B

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • CUTL1
  • CREB
  • deltaCREB
  • STAT5A
  • TBP
  • TFIID
  • HFH-1

Tissue specificity:

Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.

Enzyme Regulation:

Activated by ADP.

Molecular Function:

  • 5'-Nucleotidase Activity
  • Magnesium Ion Binding
  • Nucleotide Binding

Biological Processes:

  • Purine Nucleotide Catabolic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| cytosolic 5'-nucleotidase 1B| 5'nucleotidase| AIRP| autoimmune infertility-related protein| CB1_001512030| CN1B| CN-IB| cytosolic 5-nucleotidase 1B| cytosolic 5'-nucleotidase IB| H920_16386| I79_009773| PAL_GLEAN10020171| PANDA_002982| Rdh14| retinol dehydrogenase 14 (all-trans/9-cis/11-cis)| retinol dehydrogenase 14 (all-trans and 9-cis)| testicular tissue protein Li 1| TREES_T100010449| nt5c1b

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